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A new study reveals the negative effects of traffic noise on frogs and how some frogs have adapted. Traffic noise is stressful to frogs and impairs the production of skin peptides that defend against pathogens like chytrid fungus. Frogs from ponds near noisy highways show a dampened stress response and altered immune profile when exposed to noise compared to frogs from quiet ponds, suggesting they have adapted to reduce the negative effects of traffic noise.